Genetic risk science
We build genetic risk models for the highest-burden diseases.
PolyCypher Health builds disease risk prediction models that read the quiet signals long before symptoms appear.
Informational and Research Use Only. Our models estimate health risk. They do not diagnose or predict whether a person will develop a condition.
Where to go
Why we do this
Most healthcare begins after symptoms appear. For many serious diseases, the risk can be seen long before that.
Our mission is earlier awareness of the highest-burden diseases, so the right conversation with a clinician can happen sooner.
From genotype to absolute risk
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Genotype
A genotyping microarray reads a large set of known positions.
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Impute
Reference panels fill in the variants between known positions.
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Score
Published polygenic scores, adjusted for genetic ancestry.
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Estimate
Absolute risk over a stated period, from scores, age and sex.
Conditions we report on today
- Type 2 diabetes
- Hypertension
- Coronary artery disease
- Atrial fibrillation
- Stroke
- Chronic obstructive pulmonary disease
- Chronic kidney disease
- Alzheimer’s disease
- Major depressive disorder
- Obesity
- Colorectal cancer
- Breast cancer
- Prostate cancer
Consumer product
Priora
Priora is our consumer product: a cheek swab or a DNA file, turned into a report of estimated health risk to bring to your doctor. A combined estimate adds health and lifestyle data.
Priora is Informational and Research Use Only and is not FDA approved.
, opens in a new tab How we look after your data
Your data is encrypted at rest and in transit. We do not sell your personal or genetic data.
Talk to the team
Research, partnerships or investment: tell us what you are working on.