Precision Health Intelligence

We build disease risk models for the highest-burden diseases.

PolyCypher Health is bringing benevolent AI to the world. We develop the algorithms to build the most accurate disease risk prediction models for common diseases.

Informational and Research Use Only. Our models estimate health risk. They do not diagnose or predict whether a person will develop a condition.

Where to go

A modern medical center building in morning light.

Health enterprises and clinics

Portal access, and what is available now.

For clinics
Gloved hands using a pipette over a well plate.

Life sciences

Research partnerships for biotech, diagnostics and biopharma.

Read about the program
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Scientists

How the models work and how they were evaluated.

Read the science
The Priora DNA collection kit box beside its instruction card.

Looking for Priora?

Order a DNA kit, upload a DNA file or sign in to read your report.

Visit Priora

Why we do this

The highest-burden diseases are biologically complex and poorly understood. We develop algorithms to model that complexity, because a risk model is only as useful as it is accurate.

Our mission is better disease risk models, and products built on them for people, clinicians and researchers.

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From genotype to absolute risk

  1. Genotype

    A genotyping microarray reads a large set of known positions.

  2. Impute

    Reference panels fill in the variants between known positions.

  3. Score

    Published polygenic scores, adjusted for genetic ancestry.

  4. Estimate

    Absolute risk over a stated period, from scores, age and sex.

Conditions we report on today

13 conditions grouped by body system. The list follows.
  • Type 2 diabetes
  • Hypertension
  • Coronary artery disease
  • Atrial fibrillation
  • Stroke
  • Chronic obstructive pulmonary disease
  • Chronic kidney disease
  • Alzheimer’s disease
  • Major depressive disorder
  • Obesity
  • Colorectal cancer
  • Breast cancer
  • Prostate cancer

Consumer product

Priora

Priora is our consumer product: a cheek swab or a DNA file, turned into a report of estimated health risk to bring to your doctor. A combined estimate adds health and lifestyle data.

Priora is Informational and Research Use Only and is not FDA approved.

The Priora DNA collection kit box beside its instruction card , opens in a new tab

How we look after your data

Your data is encrypted at rest and in transit. We do not sell your personal or genetic data.

Trust and privacy

Talk to the team

Research, partnerships or investment: tell us what you are working on.